ACH-702
ACH-702 is a potent anti-tubercular agent. ACH-702 also shows broad-spectrum antibacterial activity.
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- CAS No.: 922491-46-1
- Formule: C21H25FN4O3S
- Masse moléculaire:432.51
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEp-2 | CC50 |
9 μM
Compound: 7a(R)
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Cytotoxicity against human Hep2 cells after 72 hrs by alamar blue assay
Cytotoxicity against human Hep2 cells after 72 hrs by alamar blue assay
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[PMID: 21425851] |
ACH-702 shows anti-tubercular activity with the MIC50 and the MIC90 value of 0.0625 and 0.125 μg/ml for Mycobacterium tuberculosis , respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 922491-46-1
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Masse moléculaire 432.51
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Formule C21H25FN4O3S
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SMILES
O=C1NSC(N(C2=C3C=C(C(N4C[C@@H](CC4)C(N)(C)C)=C2OC)F)C5CC5)=C1C3=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Molina-Torres CA, et al. In vitro activity of a new isothiazoloquinolone, ACH-702, against Mycobacterium tuberculosis and other mycobacteria. Antimicrob Agents Chemother. 2010 May;54(5):2188-90. [Content Brief]
[2]. Pucci MJ, et al. In vitro and in vivo profiles of ACH-702, an isothiazoloquinolone, against bacterial pathogens. Antimicrob Agents Chemother. 2011 Jun;55(6):2860-71. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ACH-702 Related Classifications
HY-123451 Related Classifications
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