Cy5.5 DBCO
Based on 1 publication(s) in Google Scholar
Cy5.5 DBCO is a click chemistry reagent containing an cycloalkynes group. Cy5.5 DBCO is a linker of Cyanine5.5 fluorophore. DBCO group enables copper free biocompatible click chemistry with fast reaction kinetics and good stability.
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- CAS No.: 1857352-95-4
- Formule: C59H58N4O14S4
- Masse moléculaire:1175.37
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Stockage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Activité biologique
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Chemical Information
- Protocole
- Pureté et documentation
- Références
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Cy5.5 DBCO
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Activité biologique
Description
Chemical Information
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CAS No. 1857352-95-4
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Appearance Solid
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Masse moléculaire 1175.37
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Formule C59H58N4O14S4
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Color Brown to black
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SMILES
O=C(CCCCCN1C2=CC=C3C(C=C(S(=O)(O)=O)C=C3S(=O)(O)=O)=C2C(C)(C)/C1=C\C=C\C=C\C4=[N+](CC)C5=C(C4(C)C)C(C=C(S(=O)(O)=O)C=C6S(=O)([O-])=O)=C6C=C5)NCCC(N7C8=C(C#CC9=C(C7)C=CC=C9)C=CC=C8)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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Acta Biomater
Engineered bioorthogonal cell delivery system for in situ antimicrobial peptide recruitment during systemic bacterial infection. [Abstract]2025 Apr 10:S1742-7061(25)00265-X. PMID: 40220946
Protocole
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EdU Incorporation Assay (Click Chemistry-Based DNA Synthesis Measurement)
The EdU incorporation assay measures DNA synthesis by adding the thymidine analog 5-ethynyl-2′-deoxyuridine to cells or tissues, where it is incorporated into newly synthesized DNA during S phase. Incorporated EdU is detected by copper-catalyzed azide-alkyne cycloaddition, in which a fluorescent azide covalently reacts with the ethynyl group on EdU, allowing S-phase cells to be detected by fluorescence microscopy, flow cytometry, or high-content imaging. EdU detection does not require DNA denaturation or anti-BrdU antibody access, which preserves sample structure and improves compatibility with immunostaining and multiparameter cytometry compared with BrdU-based detection. EdU can be cytotoxic in a cell-type- and exposure-dependent manner, so pulse duration, concentration, and continuous-labeling designs should be validated for each cell type.
Pureté et documentation
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Fiche technique (273 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Instruction de manipulation (2659 KB)
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Cy5.5 DBCO Related Classifications
HY-151720 Related Classifications
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