Sp4 - trans-acting transcription factor 4 Gene

Also Known as HF-1b; HF1-b; 5730497N03Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20688

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and identical protein binding activity. Acts upstream of or within regulation of heart contraction. Predicted to be located in cytosol and nucleoplasm. Is expressed in several structures, including alimentary system; embryo mesenchyme; genitourinary system; nervous system; and sensory organ. Used to study schizophrenia. Human ortholog(s) of this gene implicated in congenital heart disease and dilated cardiomyopathy. Orthologous to human SP4 (Sp4 transcription factor). [provided by Alliance of Genome Resources, Apr 2022]

Sp4 Products (2)

mRNA Protein Name
NM_001166385.2 NP_001159857.2 transcription factor Sp4 isoform 2
NM_009239.4 NP_033265.4 transcription factor Sp4 isoform 1

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence Références Source
acts upstream of or within regulation of heart contraction IMP
IMP: Inferred from mutant phenotype
11007485 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transcription factor Sp4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (23)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-179528 DIM-3,5-Cl2 99.18% Unkown
HY-156277 SP4f Activator 99.77% Unkown
HY-156276 SP4e Activator 99.72% Unkown
HY-482945 (SP-4-1)-[[4,4′,4′′,4′′′-(21H,23H-Porphine-5,10,15,20-tetrayl-κN21,κN22,κN23,κN24)tetrakis[benzenesulfonato]](6-)]cobaltate(3-) / Unkown
HY-RS13607 SP4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W075610 Nickelate(4-), [[4,4',4'',4'''-(21H,23H-porphine-5,10,15,20-tetrayl)tetrakis[benzoato]](6-)-N21,N22,N23,N24]-, tetrahydrogen, (SP-4-1)- / Unkown
HY-W456409 (SP-4-1)-[5,10,15,20-Tetra-4-pyridinyl-21H,23H-porphinato(2-)-κN21,κN22,κN23,κN24]nickel / Unkown
HY-W456534 Cuprate(4-), [[4,4′,4′′,4′′′-(21H,23H-porphine-5,10,15,20-tetrayl-κN21,κN22,κN23,κN24)tetrakis[benzoato]](6-)]-, (SP-4-1)- / Unkown
HY-W456551 Copper, [2,7,12,17-tetrakis(1,1-dimethylethyl)-21H,23H-porphyrazinato(2-)-κN21,κN22,κN23,κN24]-, (SP-4-1)- / Unkown
HY-W456552 (SP-4-1)-[5,10,15,20-Tetrakis(4-ethynylphenyl)-21H,23H-porphinato(2-)-κN21,κN22,κN23,κN24]zinc / Unkown
HY-W456554 Zincate(4-), [[4,4′,4′′,4′′′-(21H,23H-porphine-5,10,15,20-tetrayl-κN21,κN22,κN23,κN24)tetrakis[benzenesulfonato]](6-)]-, hydrogen (1:4), (SP-4-1)- / Unkown
HY-W456556 (SP-4-1)-[5,10,15,20-Tetraphenyl-21H,23H-porphinato(2-)-κN21,κN22,κN23,κN24]tin / Unkown
HY-W456557 (SP-4-1)-[[4,4′,4′′,4′′′-(21H,23H-Porphine-5,10,15,20-tetrayl-κN21,κN22,κN23,κN24)tetrakis[benzoato]](6-)]manganate(3-) / Unkown
HY-W456558 (SP-4-1)-[5,10,15,20-Tetrakis(4-methylphenyl)-21H,23H-porphinato(2-)-κN21,κN22,κN23,κN24]manganese / Unkown
HY-W456560 (SP-4-1)-[5,10,15,20-Tetrakis(4-methoxyphenyl)-21H,23H-porphinato(2-)-κN21,κN22,κN23,κN24]manganese / Unkown
HY-W543252 (SP-4-1)-[[4,4',4'',4'''-(21H,23H-Porphine-5,10,15,20-tetrayl-κN21,κN22,κN23,κN24)tetrakis[benzoato]](6-)]cobaltate(4-) / Unkown
HY-W543724 (SP-4-1)-[5,10,15,20-Tetrakis(4-bromophenyl)-21H,23H-porphinato(2-)-κN21,κN22,κN23,κN24]cobalt / Unkown
HY-W855971 (SP-4-1)-[29H,31H-phthalocyanine-2,9,16,23-tetracarboxylato(6-)-N29,N30,N31,N32]Nickelate(4-) / Unkown
HY-W855972 (SP-4-1)-[29H,31H-Phthalocyanine-2,9,16,23-tetracarboxylato(6-)-κN29,κN30,κN31,κN32]cobaltate(4-) / Unkown
HY-W855973 (SP-4-1)-[5,10,15,20-Tetrakis(4-bromophenyl)-21H,23H-porphinato(2-)-κN21,κN22,κN23,κN24]copper / Unkown
HY-W855974 (SP-4-1)-[5,10,15,20-Tetrakis(4-bromophenyl)-21H,23H-porphinato(2-)-κN21,κN22,κN23,κN24]nickel / Unkown
HY-RS18331 Sp4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24810 Sp4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sp4 NCBI NCBI:6671