TRAPPC14 - trafficking protein particle complex subunit 14 Gene

Also Known as MAP11; MCPH25; C7orf43

Species: Homo sapiens (human)

Gene Type: protein coding
Gene ID: 55262

Summary

Enables alpha-tubulin binding activity. Involved in cilium assembly and regulation of cell population proliferation. Located in several cellular components, including microtubule cytoskeleton; midbody; and plasma membrane. Part of TRAPPII protein complex. Implicated in primary autosomal recessive microcephaly. [provided by Alliance of Genome Resources, Apr 2022]

TRAPPC14 Products (1)

mRNA Protein Name
NM_018275.5 NP_060745.3 trafficking protein particle complex subunit 14 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Références Source
enables alpha-tubulin binding IDA
IDA: Inferred from direct assay
30715179 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
31467083 GOA
Biological Process GO Annotation Evidence Références Source
involved in cilium assembly IMP
IMP: Inferred from mutant phenotype
31467083 GOA
involved in regulation of cell population proliferation IDA
IDA: Inferred from direct assay
30715179 GOA
Cellular Component GO Annotation Evidence Références Source
part of TRAPPII protein complex IMP
IMP: Inferred from mutant phenotype
31467083 GOA
located in midbody IDA
IDA: Inferred from direct assay
30715179 GOA
located in mitotic spindle IDA
IDA: Inferred from direct assay
30715179 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

trafficking protein particle complex subunit 14

  • microtubule associated protein 11

  • trafficking protein particle complex 14

  • uncharacterized protein C7orf43

TRAPPC14 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Références
Intra
TRAPPC14 Q8WVR3 KRTAP6-1 Homo sapiens Q3LI64
Y2H Prey Pooling
32296183
Intra
TRAPPC14 Q8WVR3 KRTAP6-1 Homo sapiens Q3LI64
Y2H Array
32296183
Intra
TRAPPC14 Q8WVR3 NOTCH2NLC Homo sapiens P0DPK4
Y2H Prey Pooling
32296183
Intra
TRAPPC14 Q8WVR3 NOTCH2NLC Homo sapiens P0DPK4
Y2H Array
32296183
Intra
TRAPPC14 Q8WVR3 TGM1 Homo sapiens P22735
Y2H Prey Pooling
32296183
Intra
TRAPPC14 Q8WVR3 TGM1 Homo sapiens P22735
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS14985 TRAPPC1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14986 TRAPPC11 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14987 TRAPPC12 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14991 TRAPPC4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19288 Trappc4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25778 Trappc4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown