Norchelerythrine
Norchelerythrine is an alkaloid isolated from the roots of Zanthoxylum capense with antibacterial activity against gram-positive and gram-negative bacteria. Norchelerythrine exhibits inhibitory activity against Staphylococcus aureus, Pseudomonas aeruginosa, and Enterococcus faecalis and Escherichia coli with MIC values >50 µg/mL.
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- CAS No.: 6900-99-8
- Formule: C20H15NO4
- Masse moléculaire:333.34
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
MIC: >50 µg/mL (Staphylococcus aureus, Pseudomonas aeruginosa, and Enterococcus faecalis and Escherichia coli)[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HCT-116 | IC50 |
>10 μM
Compound: 3a
|
Antiproliferative activity against human HCT116 cells assessed as inhibition of cell viability after 48 hrs by MTT assay
Antiproliferative activity against human HCT116 cells assessed as inhibition of cell viability after 48 hrs by MTT assay
|
[PMID: 26026362] |
| HL-60 | IC50 |
>10 μM
Compound: 3a
|
Antiproliferative activity against human HL60 cells assessed as inhibition of cell viability after 48 hrs by WST-1 assay
Antiproliferative activity against human HL60 cells assessed as inhibition of cell viability after 48 hrs by WST-1 assay
|
[PMID: 26026362] |
Chemical Information
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CAS No. 6900-99-8
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Masse moléculaire 333.34
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Formule C20H15NO4
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SMILES
COC1=C(OC)C2=CN=C3C(C(C=CC3=C2C=C1)=C4)=CC5=C4OCO5
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Structure Classification
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Initial Source
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)