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Cat. No.: HY-10867

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PF-622

1 Cited Publications

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Based on 1 publication(s) in Google Scholar

PF-622 is a selective FAAH inhibitor, and can be used for study of analgesic and anxiolytic/antidepressant.

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CAS No.: 898235-65-9
Formule: C₂₁H₂₂N₄O
Masse moléculaire:346.43

Stockage:

Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

Data Sheet (264 KB)

PF-622 Chemical Structure

CAS No.: 898235-65-9

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Cellular Effect
Chemical Information
Publications (1)
Pureté et documentation
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Activité biologique

Description

PF-622 is a selective FAAH inhibitor, and can be used for study of analgesic and anxiolytic/antidepressant^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
HEK293	EC₅₀	>25 μM Compound: PF-622	Antagonist activity at human TRPA1 expressed in HEK293 cells assessed as decrease in intracellular calcium level Antagonist activity at human TRPA1 expressed in HEK293 cells assessed as decrease in intracellular calcium level	[PMID: 19875281]
HEK293	IC₅₀	>10 μM Compound: PF-622	Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as decrease in intracellular calcium level Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as decrease in intracellular calcium level	[PMID: 19875281]

Chemical Information

CAS No. 898235-65-9
Appearance Solid
Masse moléculaire 346.43
Formule C₂₁H₂₂N₄O
SMILES

O=C(N1CCN(CC1)CC2=NC3=C(C=C2)C=CC=C3)NC4=CC=CC=C4
Livraison

Room temperature in continental US; may vary elsewhere.

Stockage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Publications (1)

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Chin Med

Electroacupuncture to point Baihui confers anxiolytic effects by promoting oxytocin release from PVN in Mice. [Abstract]

2026 Jan 13;21(1):30. PMID: 41530867

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Ahn K, et al. Novel mechanistic class of fatty acid amide hydrolase inhibitors with remarkable selectivity. Biochemistry. 2007;46(45):13019-13030. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

PF-622

1 Cited Publications

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Activité biologique
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PF-622

High-Throughput Bioactive Compound Library

Publications Citing Use of MedChemExpress (MCE) PF-622

Activité biologique

Chemical Information

Publications (1)

Pureté et documentation

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PF-622

High-Throughput Bioactive Compound Library

Publications Citing Use of MedChemExpress (MCE) PF-622

Activité biologique

Chemical Information

Publications (1)

Pureté et documentation

Références

Calculators

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PF-622 Related Classifications

HY-10867 Related Classifications