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Cat. No.: HY-125631

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Cyclothialidine

(Synonyms: Ro 09-1437)

Cyclothialidine ( Ro 09-1437) is a potent DNA gyrase inhibitor isolated from Streptomyces filipinensisNR0484.

For research use only. We do not sell to patients.

CAS No.: 147214-63-9
Formula: C₂₆H₃₅N₅O₁₂S
Molecular Weight:641.65

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

Cyclothialidine Chemical Structure

CAS No.: 147214-63-9

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Cyclothialidine ( Ro 09-1437) is a potent DNA gyrase inhibitor isolated from Streptomyces filipinensisNR0484^[1].

All DNA/RNA Synthesis Isoforms :

Chemical Information

CAS No. 147214-63-9
Molecular Weight 641.65
Formula C₂₆H₃₅N₅O₁₂S
SMILES

O=C(N[C@@H](CSCC1=C(O)C=C(O)C(C)=C1C(OC2)=O)C(N[C@@H](C)C(O)=O)=O)[C@H]2NC([C@H]3N(CC[C@H]3O)C([C@@H](N)CO)=O)=O
Synonyms

Ro 09-1437
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Angehrn P, et al. New antibacterial agents derived from the DNA gyrase inhibitor cyclothialidine. J Med Chem. 2004;47(6):1487-1513. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
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Chemical Information
Purity & Documentation
References

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Cyclothialidine

All DNA/RNA Synthesis Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Cyclothialidine Related Classifications

HY-125631 Related Classifications