CYP17A1-IN-2
CYP17A1-IN-2 is a potent inhibitor of CYP17A1. CYP17A1-IN-2 exhibits anti-proliferative activity against prostate cancer cells. CYP17A1-IN-2 can be used in research related to castration-resistant prostate cancer.
For research use only. We do not sell to patients.
- Formula: C23H21NO3
- Molecular Weight:359.42
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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CYP17A1 |
CYP17A1-IN-2 (Compound 14c) potently inhibits the proliferation of PC-3 and LNCaP prostate cancer cells, with GI50 values of 8.9 nM and 30.5 nM, respectively[1].
CYP17A1-IN-2 (250 nM) inhibits CYP17A by 31% in mouse testicular homogenates[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 359.42
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Formula C23H21NO3
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SMILES
O=C1OC2=CC(O)=CC=C2C3=C1C(CC=C4C5=CN=CC(C)=C5)[C@]4(C)CC3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CYP17A1-IN-2 Related Classifications
HY-181045 Related Classifications
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