[D-Leu-4]-OB3
Based on 1 Customer Validation
[D-Leu-4]-OB3 inhibits expressions of pro-inflammatory, proliferative and metastatic genes and PD-L1 expression. [D-Leu-4]-OB3 stimulates expression of pro-apoptotic genes.
For research use only. We do not sell to patients.
- Purity: 98.93%
- CAS No.: 289056-32-2
- Formula: C29H50N8O12S
- Molecular Weight:734.82
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
Chemical Information
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CAS No. 289056-32-2
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Appearance Solid
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Molecular Weight 734.82
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Formula C29H50N8O12S
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Color White to off-white
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Sequence
Ser-Cys-Ser-{D-Leu}-Pro-Gln-Thr
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Sequence Shortening
SCS-{D-Leu}-PQT
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 50 mg/mL (68.04 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (276 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.3609 mL | 6.8044 mL | 13.6088 mL | 34.0219 mL |
| 5 mM | 0.2722 mL | 1.3609 mL | 2.7218 mL | 6.8044 mL | |
| 10 mM | 0.1361 mL | 0.6804 mL | 1.3609 mL | 3.4022 mL | |
| 15 mM | 0.0907 mL | 0.4536 mL | 0.9073 mL | 2.2681 mL | |
| 20 mM | 0.0680 mL | 0.3402 mL | 0.6804 mL | 1.7011 mL | |
| 25 mM | 0.0544 mL | 0.2722 mL | 0.5444 mL | 1.3609 mL | |
| 30 mM | 0.0454 mL | 0.2268 mL | 0.4536 mL | 1.1341 mL | |
| 40 mM | 0.0340 mL | 0.1701 mL | 0.3402 mL | 0.8505 mL | |
| 50 mM | 0.0272 mL | 0.1361 mL | 0.2722 mL | 0.6804 mL | |
| 60 mM | 0.0227 mL | 0.1134 mL | 0.2268 mL | 0.5670 mL |