Dabigatran acyl-β-D-glucuronide
Dabigatran acyl-β-D-glucuronide is an active metabolite of the thrombin inhibitor Dabigatran (HY-10163). Dabigatran acyl-β-D-glucuronide increases activated partial thromboplastin time (aPTT) in isolated human platelet-poor plasma.
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- CAS. Nr.: 1015167-40-4
- Formel: C31H33N7O9
- Molecular Weight:647.64
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Biologische Aktivität
Beschreibung
Chemical Information
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CAS. Nr. 1015167-40-4
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Molecular Weight 647.64
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Formel C31H33N7O9
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SMILES
CN1C2=CC=C(C=C2N=C1CNC3=CC=C(C=C3)C(N)=N)C(N(C4=NC=CC=C4)CCC(O[C@@H]5O[C@@H]([C@H]([C@@H]([C@H]5O)O)O)C(O)=O)=O)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Eisert, W.G., Hauel, N., Stangier, J., et al. Dabigatran: An oral novel potent reversible nonpeptide inhibitor of thrombin. Arterioscler. Thromb. Vasc. Biol. 30(10), 1885-1889 (2010). [Content Brief]
[2]. Ebner, T., Wagner, K., and Wienen, W. Dabigatran acylglucuronide, the major human metabolite of dabigatran: In vitro formation, stability, and pharmacological activity. Drug. Metab. Dispos. 38(9), 1567-1575 (2010). [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Dabigatran acyl-β-D-glucuronide Related Classifications
HY-122813 Related Classifications
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