ARN19689
ARN19689 is a potent, selective, orally active and non-covalent inhibitor of N Acylethanolamine-Hydrolyzing Acid Amidase (NAAA), with an IC50 of 42 nM. ARN19689 is a promising pharmacological tool to be further investigated in the field of inflammatory conditions.
For research use only. We do not sell to patients.
- CAS No.: 2320521-34-2
- Formula: C19H27N5O4S
- Molecular Weight:421.51
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
IC50: 42 nM (N Acylethanolamine-Hydrolyzing Acid Amidase)[1]
In Vitro
ARN19689 (30 μM) inhibits the activity of human FAAH and human acid ceramidase by 25 and 34%, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 2320521-34-2
-
Molecular Weight 421.51
-
Formula C19H27N5O4S
-
SMILES
O=S(N1[C@@H]2C[C@H](C[C@H]1CC2)OC3=NC=C(COCC)N=C3)(C4=C(C)NN=C4C)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)