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Cat. No.: HY-114071

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BMS270394

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Based on 1 Customer Validation

BMS270394 is a nuclear retinoic acid receptor (RAR-γ) agonist with the EC₅₀ values of 30 nM and 400 nM for humanRAR-γ and RAR-β, respectively.

For research use only. We do not sell to patients.

Purity: 98.0%
CAS No.: 262433-54-5
Formula: C₂₃H₂₆FNO₄
Molecular Weight:399.46

Storage:

Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month

BMS270394 Chemical Structure

CAS No.: 262433-54-5

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

BMS270394 is a nuclear retinoic acid receptor (RAR-γ) agonist with the EC₅₀ values of 30 nM and 400 nM for humanRAR-γ and RAR-β, respectively^[1].

IC₅₀ & Target

RXR γ

30 nM (EC₅₀)

RXR β

400 nM (EC₅₀)

All RAR/RXR Isoforms :

Chemical Information

CAS No. 262433-54-5
Appearance Solid
Molecular Weight 399.46
Formula C₂₃H₂₆FNO₄
Color White to off-white
SMILES

CC1(C2=CC([C@@H](O)C(NC3=C(C=C(C=C3)C(O)=O)F)=O)=CC=C2C(C)(CC1)C)C
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Klaholz BP, et al. Enantiomer discrimination illustrated by high-resolution crystal structures of the human nuclear receptor hRARgamma. Proc Natl Acad Sci U S A. 2000;97(12):6322-6327. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Amount: USD 0.00

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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BMS270394

High-Throughput Bioactive Compound Library

All RAR/RXR Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

BMS270394 Related Classifications

HY-114071 Related Classifications