HIPS probe-1
Based on 1 Customer Validation
HIPS probe-1 (Compound 1) is a click chemistry reagent containing a alkyne group. HIPS probe-1 can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. HIPS probe-1 can be used as a chemical probe to specifically recognize and label aldehyde functional groups in DNA, especially abasic sites (AP sites) for DNA damage research.
For research use only. We do not sell to patients.
- Purity : 95.04%
- CAS No.: 2490429-83-7
- Formula: C13H15N3
- Molecular Weight:213.28
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Storage:
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Biological Activity
Description
Chemical Information
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CAS No. 2490429-83-7
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Appearance Solid
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Molecular Weight 213.28
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Formula C13H15N3
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Color White to light yellow
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SMILES
C#CCN1C2=C(C=C1CN(C)N)C=CC=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (468.87 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.6887 mL | 23.4434 mL | 46.8867 mL | 117.2168 mL |
| 5 mM | 0.9377 mL | 4.6887 mL | 9.3773 mL | 23.4434 mL | |
| 10 mM | 0.4689 mL | 2.3443 mL | 4.6887 mL | 11.7217 mL | |
| 15 mM | 0.3126 mL | 1.5629 mL | 3.1258 mL | 7.8145 mL | |
| 20 mM | 0.2344 mL | 1.1722 mL | 2.3443 mL | 5.8608 mL | |
| 25 mM | 0.1875 mL | 0.9377 mL | 1.8755 mL | 4.6887 mL | |
| 30 mM | 0.1563 mL | 0.7814 mL | 1.5629 mL | 3.9072 mL | |
| 40 mM | 0.1172 mL | 0.5861 mL | 1.1722 mL | 2.9304 mL | |
| 50 mM | 0.0938 mL | 0.4689 mL | 0.9377 mL | 2.3443 mL | |
| 60 mM | 0.0781 mL | 0.3907 mL | 0.7814 mL | 1.9536 mL | |
| 80 mM | 0.0586 mL | 0.2930 mL | 0.5861 mL | 1.4652 mL | |
| 100 mM | 0.0469 mL | 0.2344 mL | 0.4689 mL | 1.1722 mL |