Hycanthone (Standard)
Hycanthone (Standard) is the analytical standard of Hycanthone (HY-B1099). This product is intended for research and analytical applications. Hycanthone is an apurinic/apyrimidinic endonuclease 1 (APE1) inhibitor, DNA intercalator and Antischistosomal agent, with an IC50 of 80 nM against APE1. Hycanthone irreversibly inhibits thymidine incorporation into DNA in adult sensitive *Schistosoma mansoni*, while exerts weak inhibitory effects on uridine and leucine incorporation. Hycanthone reduces influenza virus-induced interferon production. Hycanthone exhibits mutagenic effects in various organisms, shows teratogenicity in mice and rabbits, and induces neoplastic liver lesions in partially hepatectomized mice. Hycanthone can be used in research related to schistosomiasis and cancer.
For research use only. We do not sell to patients.
- Purity : 98%
- CAS No.: 3105-97-3
- Formula: C20H24N2O2S
- Molecular Weight:356.48
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Purity & Documentation
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Help & FAQs
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 3105-97-3
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Molecular Weight 356.48
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Formula C20H24N2O2S
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SMILES
O=C1C2=C(SC3=C1C=CC=C3)C(CO)=CC=C2NCCN(CC)CC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Hycanthone (Standard) Related Classifications
HY-B1099R Related Classifications
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Keywords
- Hycanthone (Standard)
- 3105-97-3
- Reference Standards
- DNA/RNA Synthesis
- DNA Alkylator/Crosslinker
- Parasite
- IFNAR
- Interferon-α/β receptor
- Interferon-alpha/beta receptor
- clone 1-5c-4 cells
- rat embryo cells
- LLC-MK2 cells
- U251-MG glioblastoma multiforme
- Apurinic Endonuclease-1
- mice
- rabbits
- schistosomiasis
- influenza virus
- Schistosoma mansoni
- Inhibitor
- inhibitor
- inhibit