Denfivontinib hydrochloride
Based on 2 publication(s) in Google Scholar
Denfivontinib (G-749) hydrochloride is an AXL inhibitor that has synergistic antitumor effects with the PD-1 inhibitor Pembrolizumab (HY-P9902). Denfivontinib can enhance the NOD-like receptor pathway, thereby promoting the formation of the NLRP3 inflammasome.
For research use only. We do not sell to patients.
- CAS No.: 1457983-33-3
- Formula: C25H26BrClN6O2
- Molecular Weight:557.87
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Publications Citing Use of MedChemExpress (MCE) Denfivontinib hydrochloride
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Biological Activity
Chemical Information
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CAS No. 1457983-33-3
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Molecular Weight 557.87
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Formula C25H26BrClN6O2
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SMILES
O=C1NC=C(C2=C1C(NC3=CC=C(C=C3)OC4=CC=CC=C4)=NC(NC5CCN(CC5)C)=N2)Br.Cl
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Synonyms
G-749 hydrochloride
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (2)
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Journal Impact Factor
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Most Recent
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Adv Sci (Weinh)
NAT10 Increases Lysosomal Acidification to Promote Esophageal Cancer Metastasis via ac4C Acetylation of ATP6V0E1 mRNA. [Abstract]2025 Aug;12(31):e02931. PMID: 40729677 -
Anal Chem
Exposome-Scale Investigation of Cl-/Br-Containing Chemicals Using High-Resolution Mass Spectrometry, Multistage Machine Learning, and Cloud Computing. [Abstract]2025 Jun 3;97(21):11099-11109. PMID: 40401576
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Denfivontinib hydrochloride Related Classifications
HY-W400801 Related Classifications
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