Deruxtecan-Eribulin 

Deruxtecan-Eribulin is a Drug-Linker Conjugates for ADC, which is composed of a linker and a toxic molecule Exatecan (HY-13631) (DNA topoisomerase I inhibitor) and Eribulin (HY-13442) (Microtubule inhibitor). Deruxtecan-Eribulin can be used for ADC synthesis.

2372.59

C₁₂₂H₁₅₁FN₁₆O₃₂

Solid

Off-white to light yellow

C=C1C[C@@]2([H])O[C@@]1([H])CC[C@]3([H])O[C@](C([C@H](C)C3)=C)([H])C[C@@]4([H])[C@]([C@@H](OC)[C@@H](C[C@H](O)CNC(OCC5=CC=C(NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(COC6=CC=C(CC(NC(CCCCCN7C(C=CC7=O)=O)=O)C(NCC(NCC(N[C@@H](CC8=CC=CC=C8)C(NCC(NCOCC(N[C@@H]9C%10=C%11C(C(N%12C%11)=CC([C@](O)(C(OC%13)=O)CC)=C%13C%12=O)=NC%14=CC(F)=C(C)C(CC9)=C%14%10)=O)=O)=O)=O)=O)=O)C=C6)=O)=O)=O)C=C5)=O)O4)([H])CC(C[C@]%15([H])O[C@]%16([H])[C@]%17([H])O[C@@]%18(O[C@@]%19([H])[C@@](O[C@]%17([H])[C@@]%19([H])O[C@@]%16([H])CC%15)([H])C%18)CC2)=O

Room temperature in continental US; may vary elsewhere.

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.