2. GPCR/G Protein Neuronal Signaling
  3. mGluR
  4. Desmethyl-YM-298198

Desmethyl-YM-298198 is a high-affinity, selective, and noncompetitive mGluR1 antagonist (IC50: 16 nM). Desmethyl-YM-298198 has analgesic effect in Streptozotocin (HY-13753)-induced hyperalgesic mice.

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Desmethyl-YM-298198

Desmethyl-YM-298198 Estructura química

No. CAS : 299901-57-8

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Descripciòn

Desmethyl-YM-298198 is a high-affinity, selective, and noncompetitive mGluR1 antagonist (IC50: 16 nM). Desmethyl-YM-298198 has analgesic effect in Streptozotocin (HY-13753)-induced hyperalgesic mice[1].

Peso molecular

328.43

Fòrmula

C17H20N4OS
No. CAS
SMILES

O=C(C1=C(C)N2C3=CC(N)=CC=C3N=C2S1)NC4CCCCC4
Envío

Room temperature in continental US; may vary elsewhere.
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Desmethyl-YM-298198 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Desmethyl-YM-298198299901-57-8mGluRMetabotropic glutamate receptorsanalgesicStreptozotocinhyperalgesicneurological disorderInhibitorinhibitorinhibit

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Nombre del producto:
Desmethyl-YM-298198
Cat. No.:
HY-103567A
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