2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. Calcium Channel
  4. Devapamil

Devapamil  (Synonyms: D 888; Desmethoxyverapamil)

Cat. No.: HY-U00056 Purity: 99.63%
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Devapamil (D 888; Desmethoxyverapamil) is an antagonist for calcium channel.

For research use only. We do not sell to patients.

Devapamil

Devapamil Chemical Structure

CAS No. : 92302-55-1

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Devapamil Related Antibodies

Top Publications Citing Use of Products

View All Calcium Channel Isoform Specific Products:

View All Isoforms
N-type calcium channel L-type calcium channel P/Q-type calcium channel T-type calcium channel Calcium Channel

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Description

Devapamil (D 888; Desmethoxyverapamil) is an antagonist for calcium channel[1].

Molecular Weight

424.58

Formula

C26H36N2O3
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

N#CC(CCCN(CCC1=CC(OC)=CC=C1)C)(C(C)C)C2=CC=C(C(OC)=C2)OC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (117.76 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3553 mL 11.7763 mL 23.5527 mL
5 mM 0.4711 mL 2.3553 mL 4.7105 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.3553 mL 11.7763 mL 23.5527 mL 58.8817 mL
5 mM 0.4711 mL 2.3553 mL 4.7105 mL 11.7763 mL
10 mM 0.2355 mL 1.1776 mL 2.3553 mL 5.8882 mL
15 mM 0.1570 mL 0.7851 mL 1.5702 mL 3.9254 mL
20 mM 0.1178 mL 0.5888 mL 1.1776 mL 2.9441 mL
25 mM 0.0942 mL 0.4711 mL 0.9421 mL 2.3553 mL
30 mM 0.0785 mL 0.3925 mL 0.7851 mL 1.9627 mL
40 mM 0.0589 mL 0.2944 mL 0.5888 mL 1.4720 mL
50 mM 0.0471 mL 0.2355 mL 0.4711 mL 1.1776 mL
60 mM 0.0393 mL 0.1963 mL 0.3925 mL 0.9814 mL
80 mM 0.0294 mL 0.1472 mL 0.2944 mL 0.7360 mL
100 mM 0.0236 mL 0.1178 mL 0.2355 mL 0.5888 mL
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Devapamil Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Devapamil92302-55-1D 888 DesmethoxyverapamilD888D-888Calcium ChannelCa2+ channelsCa channelsInhibitorinhibitorinhibit

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