DJ-53
DJ-53 (compund 68) is an orally active phenylquinoline-based soluble epoxide hydrolase inhibitor.
For research use only. We do not sell to patients.
- Formula: C26H22F3N3O4
- Molecular Weight:497.47
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Epoxide Hydrolase[1]
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HEK-293T | IC50 |
>200 μM
Compound: 68; DJ-53
|
Cytotoxicity against HEK293T cells incubated for 48 hrs by CCK8 assay
Cytotoxicity against HEK293T cells incubated for 48 hrs by CCK8 assay
|
[PMID: 39361006] |
| HepG2 | IC50 |
>200 μM
Compound: 68; DJ-53
|
Cytotoxicity against human HepG2 cells incubated for 48 hrs by CCK8 assay
Cytotoxicity against human HepG2 cells incubated for 48 hrs by CCK8 assay
|
[PMID: 39361006] |
Chemical Information
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Molecular Weight 497.47
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Formula C26H22F3N3O4
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SMILES
COC1=CC(C2=CC3=CC=C(C=C3N=C2)NC(NCC4=CC=C(C=C4)OC(F)(F)F)=O)=CC(OC)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)