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United States

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Art. -Nr.: HY-168144

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DJ-53

DJ-53 (compund 68) is an orally active phenylquinoline-based soluble epoxide hydrolase inhibitor.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

Formel: C₂₆H₂₂F₃N₃O₄
Molecular Weight:497.47

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

DJ-53 Chemical Structure

Größe

Preis

Verfügbarkeit

Menge

Amount: USD 0.00

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- Cellular Effect
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

DJ-53 (compund 68) is an orally active phenylquinoline-based soluble epoxide hydrolase inhibitor^[1].

IC₅₀ & Target

Epoxide Hydrolase^[1]

Cellular Effect

Cell Line	Type	Value	Description	References
HEK-293T	IC₅₀	>200 μM Compound: 68; DJ-53	Cytotoxicity against HEK293T cells incubated for 48 hrs by CCK8 assay Cytotoxicity against HEK293T cells incubated for 48 hrs by CCK8 assay	[PMID: 39361006]
HepG2	IC₅₀	>200 μM Compound: 68; DJ-53	Cytotoxicity against human HepG2 cells incubated for 48 hrs by CCK8 assay Cytotoxicity against human HepG2 cells incubated for 48 hrs by CCK8 assay	[PMID: 39361006]

Chemical Information

Molecular Weight 497.47
Formel C₂₆H₂₂F₃N₃O₄
SMILES

COC1=CC(C2=CC3=CC=C(C=C3N=C2)NC(NCC4=CC=C(C=C4)OC(F)(F)F)=O)=CC(OC)=C1
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Ding J, et al. Discovery of Orally Active Phenylquinoline-Based Soluble Epoxide Hydrolase Inhibitors with Anti-Inflammatory and Analgesic Activity. J Med Chem. 2024 Oct 24;67(20):18412-18447. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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