Pard6b - par-6 family cell polarity regulator beta Gene

Also Known as Par6b

Species: Mus musculus

Gene Type: protein coding
Gene ID: 58220

Summary

Predicted to enable protein kinase C binding activity. Predicted to be involved in several processes, including centrosome cycle; establishment or maintenance of cell polarity; and protein-containing complex assembly. Predicted to act upstream of or within cell division. Located in several cellular components, including apical plasma membrane; bicellular tight junction; and cell cortex. Is expressed in blastocyst; early conceptus; egg cylinder; and lung epithelium. Orthologous to human PARD6B (par-6 family cell polarity regulator beta). [provided by Alliance of Genome Resources, Apr 2022]

Pard6b Products (1)

mRNA Protein Name
NM_021409.2 NP_067384.2 partitioning defective 6 homolog beta

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
10934474 MGI
Cellular Component GO Annotation Evidence References Source
located in apical part of cell IDA
IDA: Inferred from direct assay
15950600 MGI
located in apical plasma membrane IDA
IDA: Inferred from direct assay
22333836 MGI
located in bicellular tight junction IDA
IDA: Inferred from direct assay
15950600 MGI
located in cell cortex IDA
IDA: Inferred from direct assay
15950600 MGI
located in nucleus IDA
IDA: Inferred from direct assay
15950600 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

partitioning defective 6 homolog beta

  • PAR-6 beta

  • PAR-6B

  • par-6 (partitioning defective 6) homolog beta

  • partitioning-defective protein 6, beta

Pard6b Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Cross
Pard6b Q9JK83 CDC42 Homo sapiens P60953
Y2H
10934474
Cross
Pard6b Q9JK83 CDC42 Homo sapiens P60953
FRET
12606577
Cross
Pard6b Q9JK83 PARD3 Homo sapiens Q8TEW0
CoIP
10934474
Cross
Pard6b Q9JK83 PARD3 Homo sapiens Q8TEW0
Anti Tag CoIP
26496610
Cross
Pard6b Q9JK83 PARD3 Homo sapiens Q8TEW0
Pull Down
10934474
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10039 PARD6B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pard6b NCBI NCBI:84612