ACTR6 - actin related protein 6 Gene

Also Known as ARP6; CDA12; hARP6; hARPX; HSPC281; MSTP136

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 64431

About ACTR6

Cytogenetic location: 12q23.1 Genomic coordinates (GRCh38): 12:100,200,815-100,224,424 (from NCBI)

This gene has 13 transcripts (splice variants), 215 orthologues and 26 paralogues. Ubiquitous expression in brain (RPKM 10.9), testis (RPKM 9.8) and 25 other tissues.

Summary

Predicted to enable nucleosome binding activity. Predicted to be involved in histone exchange. Predicted to be located in nucleus. Predicted to be part of Swr1 complex. [provided by Alliance of Genome Resources, Apr 2022]

ACTR6 Products (1)

mRNA Protein Name
NM_022496.5 NP_071941.1 actin-related protein 6

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
15647280 GOA
Biological Process GO Annotation Evidence References Source
involved in nucleolus organization IMP
IMP: Inferred from mutant phenotype
26164235 GOA
Cellular Component GO Annotation Evidence References Source
located in nucleolus IDA
IDA: Inferred from direct assay
26164235 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ACTR6 Protein Structure

Actin

Actin: Actin (2 - 394)

  • 0
  • 100
  • 200
  • 300
  • 396 a.a.
Protein Preferred Names Protein Names

actin-related protein 6

  • ARP6 actin related protein 6 homolog

ACTR6 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
ACTR6 Q9GZN1 H2AZ1 Homo sapiens P0C0S5
Anti Bait CoIP
20473270
Intra
ACTR6 Q9GZN1 ZNHIT1 Homo sapiens O43257
Anti Bait CoIP
20473270
Intra
ACTR6 Q9GZN1 ZNHIT1 Homo sapiens O43257
Anti Tag CoIP
28514442
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00234 ACTR6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22376 Actr6 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28900 Actr6 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta ACTR6 VGNC VGNC:69521
Rattus norvegicus ACTR6 RGD RGD:1304609
Canis familiaris ACTR6 VGNC VGNC:37556
Felis catus ACTR6 VGNC VGNC:59559
Mus musculus ACTR6 MGD MGI:1914269
Bos taurus ACTR6 VGNC VGNC:25588
Others ACTR6 NCBI