MMV688844
MMV688844 is a potent Mycobacterium abscessus (Mabs) DNA Gyrase inhibitor with an IC50 value of 2 μM. MMV688844 has bactericidal properties against Mabs bamboo with a MIC50 of 12 μM. MMV688844 can be used for researching anti-bacteria.
For research use only. We do not sell to patients.
- CAS No.: 2650213-59-3
- Formula: C23H25ClN4O2
- Molecular Weight:424.92
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All DNA/RNA Synthesis Isoforms
More
Biological Activity
IC50: 2 μM (Mabs DNA Gyrase)[1]
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HeLa | IC50 |
>25 μM
Compound: 47; MMV688844
|
Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 48 hrs by resazurin dye based fluorescence assay
Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 48 hrs by resazurin dye based fluorescence assay
|
[PMID: 30647879] |
Chemical Information
-
CAS No. 2650213-59-3
-
Molecular Weight 424.92
-
Formula C23H25ClN4O2
-
SMILES
O=C(C1CCN(CCC2=CC=C(Cl)C=C2)CC1)NC3=CC=NC4=CC=C(OC)N=C34
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)