DNA-PK-IN-5
DNA-PK-IN-5 is a potent inhibitor of DNA-PK. DNA-PK-IN-5 inhibits DNA-PKcs activity, thus greatly reducing tumor DNA repair and inducing cells to enter the apoptotic program. DNA-PK-IN-5 enhances the sensitivity of tumor tissues to radiotherapy, overcomes the problem of agent resistance, and enhances the inhibitory effect on a variety of solid tumors and hematological tumors (extracted from patent WO2021204111A1, compound 2).
For research use only. We do not sell to patients.
- CAS No.: 2719736-43-1
- Formula: C21H22N8O2
- Molecular Weight:418.45
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 2719736-43-1
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Molecular Weight 418.45
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Formula C21H22N8O2
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SMILES
O=C1N(N2CC3OC(CC3)C2)C4=NC(NC5=C(C)C=C6N=CC=NC6=C5)=NC=C4N1C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)