DS 4574
DS 4574 is an orally active peptidoleukotriene receptor antagonist and mast cell stabilizer. DS 4574 has antiulcer, gastroprotective and antisecretory effects. DS 4574 inhibits various types of experimental asthma models. DS 4574 protects rats from endotoxin-induced intestinal injury.
For research use only. We do not sell to patients.
- CAS No.: 118314-35-5
- Formula: C13H16N6OS
- Molecular Weight:304.37
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All Leukotriene Receptor Isoforms
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Biological Activity
Chemical Information
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CAS No. 118314-35-5
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Molecular Weight 304.37
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Formula C13H16N6OS
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SMILES
O=C1C2=C(N=C3SC(CCC4CCCCC4)=NN13)N=NN2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Tabuchi Y, et al. Protective effect of DS-4574, a peptidoleukotriene receptor antagonist, against endotoxin-induced intestinal injury in rats. Eur J Pharmacol. 1995 Feb 6;273(3):281-4. [Content Brief]
[2]. Yamashika Y, et al. Antisecretory effect of DS-4574, a mast cell stabilizer with peptidoleukotriene antagonism, on gastric acid secretion in the pig. Agents Actions. 1994 Mar;41(1-2):17-20. [Content Brief]
[3]. Tabuchi Y, et al. Effect of DS-4574, a novel peptidoleukotriene antagonist with mast cell stabilizing action, on acute gastric lesions and gastric secretion in rats. Jpn J Pharmacol. 1992 Dec;60(4):335-40. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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