Other Labeling Dyes

AF647 Cadaverine is a far-red fluorescent polarity tracer. AF647 Cadaverine possesses a primary amine group that enables covalent labeling of carboxylic acids via carbodiimide activation or covalent labeling of glutamine residues through transamidation, rendering it applicable for bioconjugation, cell imaging, and blood-brain barrier permeability assays (Ex/Em = 651/670 nm).

CL-NC is a chemiluminescent probe used for in vivo imaging of N-methyl-D-aspartate receptors (NMDARs), and its detection mechanism relies on bioorthogonal activation achieved via a tetrazine-triggered click-to-release reaction. The isonitrile group of CL-NC undergoes a click reaction with tetrazine, followed by hydrolysis and β-elimination to release a phenoxide anion, which induces the departure of adamantane and generates chemiluminescence. CL-NC has a maximum absorption wavelength of approximately 425 nm, a maximum fluorescence emission wavelength of approximately 670 nm, and a maximum chemiluminescence emission wavelength of 710 nm. When used in combination with Tz-IFDL (HY-D3369), an NMDAR ligand conjugated with tetrazine, CL-NC enables targeted imaging of NMDARs in living cells, as well as in the brain and spinal cord of living mice.

Th-TMR-S-SNAP is a fluorescent probe used for SNAP-tag labeling and wash-free live-cell imaging of intracellular SNAP-tag fusion proteins. The excitation wavelength of Th-TMR-S-SNAP is 561 nm, and its emission wavelength ranges from 570 to 620 nm.

JOE phosphoramidite (6-isomer) is a derivative of JOE (dimethoxy-dichloro-carboxyfluorescein) containing a phosphoramidite moiety, used in oligonucleotide synthesis. JOE phosphoramidite (6-isomer) is primarily employed in the synthesis of fluorescent oligonucleotide probes (Ex/Em = 520/548 nm).

JOE phosphoramidite, 5-isomer is a derivative of JOE (dimethoxy-dichloro-carboxyfluorescein) containing a phosphoramidite moiety, used for oligonucleotide synthesis. JOE phosphoramidite, 5-isomer is primarily used in the synthesis of fluorescent oligonucleotide probes (Ex/Em = 520/548 nm).

5'-TAMRA C12 Amidite (5-isomer) is a TAMRA derivative featuring a phosphoramidite moiety for use in oligonucleotide synthesis. It can be used to synthesize fluorescent oligonucleotide probes (Ex/Em = 553/576 nm) .

5'-TAMRA amidite (N-TAMRA-piperidinyl), 6-carboxy single isomer, is a phosphoramidite derivative of TAMRA (tetramethylrhodamine) used in oligonucleotide synthesis. It is primarily employed in the synthesis of fluorescent oligonucleotide probes (Ex/Em = 553/576 nm).

AMCA-PEG4-acid is a derivative of AMCA featuring a carboxylic acid group for use in amide coupling reactions. It incorporates a PEG4 linker to enhance solubility and reduce steric hindrance (Ex/Em = 347/444 nm).

SMCC-PE is a dipalmitoylphosphatidylethanolamine derivative modified with the heterobifunctional crosslinker SMCC. SMCC-PE is an intermediate formed by conjugating the SMCC linker with R-phycoerythrin for antibody conjugation.

BC-PEG-NH2 (CLIP-PEG-NH2) is a chemical building block specifically designed for the CLIP-tag system, featuring enhanced water solubility and reactivity. BC-PEG-NH2 can be used for the synthesis of super-resolution imaging probes.

Cross-Linked Allophycocyanin is a trimer biliprotein with maximum absorption at 650 nm.

Arg-Flipper 34 is one of the flipper probes which have been introduced as small molecule fluorophores to image membrane tension in living systems. Arg-Flipper 34 can be used to assess the mechanics of early endocytosis.

HaloFlipper 30 is a fluorescent probe that covalently reacts with HaloTag fusion proteins to form an ester bond, which allows the probe to be stably attached to membrane structures. HaloFlipper 30 has high specificity, precision and good cell permeability.

10-Octadecylacridine orange (bromide) is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.

DAz-1 is a sulfonic acid probe for living cells, which can directly detect sulfonic acid-modified proteins in living cells and is cell-permeable.

DG-8 is a potent inhibitor of STAT3-dependent transcription (IC₅₀ 0.98 μM). DG-8 is a fluorescent probe that contains a fluorescent dansyl moiety.

Citrazinic acid is a weakly fluorescent compound whose optical properties are dependent on aggregation states and chemical environment. Citrazinic acid strongly tends to form dimers at high concentrations.

Vari Fluor 532 SE (VF 532 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=532 nm/545 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.

Vari Fluor 660 SE (VF 660 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=660 nm/679 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.

Vari Fluor 640-dUTP (VF 640-dUTP) is enzymatically incorporated into DNA/cDNA and can replace its natural counterpart, dTTP. Vari Fluor 555-dUTP can be used to produce biotinylated DNA probes in a variety of assay applications.