(E)-N-(4-Methoxyphenyl)cinnamamide
(E)-N-(4-Methoxyphenyl)cinnamamide is a selective matrix metalloproteinase inhibitor with inhibitory activity against MMP-2 (IC50 = 5.37 nM), MMP-9 (IC50 = 6.21 nM), and low activity against MMP-1 (IC50 = 5301.68 nM). (E)-N-(4-Methoxyphenyl)cinnamamide can be used for the research of tumor.
For research use only. We do not sell to patients.
- CAS No.: 76228-15-4
- Formula: C16H15NO2
- Molecular Weight:253.30
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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MMP-2 5.37 nM (IC50) |
MMP-9 6.21 nM (IC50) |
(E)-N-(4-Methoxyphenyl)cinnamamide (compound 7i) (0.1-10000 nM; 30 min) potently inhibits human recombinant MMP-2 (IC50 = 5.37 nM) and MMP-9 (IC50 = 6.21 nM) with high selectivity over human recombinant MMP-1[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 76228-15-4
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Molecular Weight 253.30
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Formula C16H15NO2
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SMILES
N(C(/C=C/C1=CC=CC=C1)=O)C2=CC=C(OC)C=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(E)-N-(4-Methoxyphenyl)cinnamamide Related Classifications
HY-W1057938 Related Classifications
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