EBOV/MARV-IN-3
EBOV/MARV-IN-3 (compound 32) is a potent EBOV and MARV inhibitor with IC50 values of 0.5, 1.2 µM, respectively. EBOV/MARV-IN-3 binds to the hydrophobic pocket close to EBOV Y517. EBOV/MARV-IN-3 shows antiviral activity.
For research use only. We do not sell to patients.
- CAS No.: 2687245-05-0
- Formula: C27H29F3N2O6
- Molecular Weight:534.52
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
|
EBOV |
MARV |
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A549 | CC50 |
68.2 μM
Compound: 32
|
Cytotoxicity against human A549 cells assessed as reduction in cell viability by Celltiter-Glo assay
Cytotoxicity against human A549 cells assessed as reduction in cell viability by Celltiter-Glo assay
|
[PMID: 32707357] |
Chemical Information
-
CAS No. 2687245-05-0
-
Molecular Weight 534.52
-
Formula C27H29F3N2O6
-
SMILES
CC1=C(C(OC2=CC(OCC(CN3CCC(CC3)C(N)=O)O)=CC=C21)=O)CC4=CC=C(C=C4)OC(F)(F)F
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Powered by Bioz