Copy Link Print Information

Efgartigimod alfa

(Synonyms: ARGX-113)
Revisión del cliente

Based on 1 Customer Validation

Efgartigimod alfa (ARGX-113) is a reversibility, humanized Fc receptor antagonist . Efgartigimod alfa is a anti FcRn monoclonal immunoglobulin G (IgG1) Fc fragment. Efgartigimod reduces serum levels of total IgG, including pathogenic autoantibodies, by blocking FcRn function without permanent impairment. Efgartigimod alfa can be used for generalised myasthenia gravis (gMG) and primary immune thrombocytopenia research.

Para uso exclusivo en investigación. No vendemos a pacientes.

  • Pureza : 98.49%
  • No. CAS: 1821402-21-4
  • Peso molecular:51.28 kDa
  • Almacenamiento:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Efgartigimod alfa
  • Experimental Validation Results for Efgartigimod alfa
  • Experimental Validation Results for Efgartigimod alfa
  • Efgartigimod alfa Chemical Structure
    Efgartigimod alfa Chemical Structure
No. CAS: 1821402-21-4
Tamaño
Precio
Stock
Cantidad
Amount: USD 0.00
Please select quantity
or
or

* Seleccione Cantidad antes de agregar artículos.

To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

Data Download
Efgartigimod alfa Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Encuentre su distribuidor local Your local distributor: Hycultec GmbHHycultec
  • Actividad biológica
  • Chemical Information
  • Pureza y Documentación
  • Referencias
  • Help & FAQs
Top Publications Citing

Use of MCE Products

Keywords

MOQ
Minimum order quantity
100 mg

Obtener un presupuesto En stock

Other size
Obtener un presupuesto
Please select quantity
Amount: USD 0.00
Sign in to MedChemExpress Inicie sesiòn
Registrar
Sign in to MedChemExpress
Registrar una cuenta nueva

At least 6 characters

Personalize your experience, you are currently not signed in. For a better experience, please create an online profile, you can:

Obtain points redemption prizes
Check out faster
Add multiple shipping locations
View orders
Assay Types
  • 1/16

    FC-GAMMA-1

  • 1/16

    Immobilized FCGRT Protein, Human (GST, HY-P72192) can bind Efgartigimod alfa. The EC50 for this effect is 535.9 ng/mL.

  • 1/16

    Flow cytometric analysis of 1X106 THP-1 cells with Efgartigimod alfa (HY-147305, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. cells without incubation with primary antibody were used as the unlabeled control (black).

  • Efgartigimod alfa Chemical Structure
    1/16
  • Efgartigimod alfa
  • Immobilized FCGRT Protein, Human (GST, HY-P72192) can bind Efgartigimod alfa. The EC50 for this effect is 535.9 ng/mL.
  • Flow cytometric analysis of 1X106 THP-1 cells with Efgartigimod alfa (HY-147305, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. cells without incubation with primary antibody were used as the unlabeled control (black).
  • FC-GAMMA-1