EGFR/HER2-IN-10
EGFR/HER2-IN-10 (compound 9F) is a potent and selective dual EGFR/HER2 inhibitor with IC50s of 2.3 nM and 234 nM for EGFR and HER2, respectively. EGFR/HER2-IN-10 shows an effective antiproliferative action against prostate carcinoma.
For research use only. We do not sell to patients.
- CAS No.: 2931499-82-8
- Formula: C29H24ClF3N6O5
- Molecular Weight:628.99
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All EGFR Isoforms
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Biological Activity
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EGFR 2.3 nM (IC50) |
HER2 234 nM (IC50) |
Chemical Information
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CAS No. 2931499-82-8
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Molecular Weight 628.99
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Formula C29H24ClF3N6O5
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SMILES
O=[N+](C1=NC=CN1CCCCOC2=CC3=C(NC4=CC=C(OC5=CC=CC(C(F)(F)F)=C5)C(Cl)=C4)N=CN=C3C=C2OC)[O-]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)