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Art. -Nr.: HY-171252

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EGFR-IN-145

Name: EGFR-IN-145
Brand: MedChemExpress
SKU: HY-171252
Price: 45.00 USD
Availability: InStock
Rating: 5 (1 reviews)

EGFR-IN-145 (compound 7c) is an EGFR kinase inhibitor. At a concentration of 20 μM, EGFR-IN-145 has an inhibition rate of 52.7% on EGFR-wild type kinase.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

CAS. Nr.: 852407-49-9
Formel: C₁₇H₁₆FN₃S
Molecular Weight:313.39

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

EGFR-IN-145 Chemical Structure

CAS. Nr.: 852407-49-9

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Biologische Aktivität

Beschreibung

EGFR-IN-145 (compound 7c) is an EGFR kinase inhibitor. At a concentration of 20 μM, EGFR-IN-145 has an inhibition rate of 52.7% on EGFR-wild type kinase^[1].

Alle EGFR Isoform-spezifische Produkte anzeigen :

Chemical Information

CAS. Nr. 852407-49-9
Molecular Weight 313.39
Formel C₁₇H₁₆FN₃S
SMILES

FC(C=C1)=CC=C1CNC2=C3C(SC4=C3CCCC4)=NC=N2
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Wu CH, et al. Design and synthesis of tetrahydropyridothieno[2,3-d]pyrimidine scaffold based epidermal growth factor receptor (EGFR) kinase inhibitors: the role of side chain chirality and Michael acceptor group for maximal potency. J Med Chem. 2010 Oct 28;53(20):7316-26. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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EGFR-IN-145

Alle EGFR Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Beschreibung

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

EGFR-IN-145 Related Classifications

HY-171252 Related Classifications

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