country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-208666

Copy Link Print Information

EGFR-IN-215

EGFR-IN-215 (Compound 019) is an EGFR inhibitor with IC₅₀ values for the L858R BaF3 and L858R/C797S mutant forms of both ≤ 0.25 μM. EGFR-IN-215 can be used in cancer research.

For research use only. We do not sell to patients.

CAS No.: 2997699-97-3
Formula: C₃₁H₃₄N₈O₂
Molecular Weight:550.65

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

EGFR-IN-215 Chemical Structure

CAS No.: 2997699-97-3

Price

Stock

Quantity

Amount: USD 0.00

* Please select Quantity before adding items.

Use of MCE Products

One-stop solution for XDC (ADC/PDC/RDC/ApDC/FDC/ISAC/VDC/SMDC)

Biological Activity

Description

EGFR-IN-215 (Compound 019) is an EGFR inhibitor with IC₅₀ values for the L858R BaF3 and L858R/C797S mutant forms of both ≤ 0.25 μM. EGFR-IN-215 can be used in cancer research^[1].

All EGFR Isoforms :

Chemical Information

CAS No. 2997699-97-3
Molecular Weight 550.65
Formula C₃₁H₃₄N₈O₂
SMILES

O=C(N1C2=C(C)C=CC=C2N(CC1)C3=CC4=C(N(C)C3=O)N=C(NC5=CC=C(N6CCN(CC6)C)C=C5)N=C4)C=C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Nathanael S., et al. Discovery of covalent egfr inhibitor through cysteine 775. WO2023196409A1.

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Dilution Calculator

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

Get Quote In-stock

Other size

Get Quote

Amount: USD 0.00

Biological Activity
- Description
Chemical Information
Purity & Documentation
References

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

Product Name:
CAS No.:
Species:
Purity:
Quantity:

EGFR-IN-215

All EGFR Isoforms