2. PROTAC JAK/STAT Signaling Protein Tyrosine Kinase/RTK
  3. Ligands for Target Protein for PROTAC EGFR
  4. EGFR ligand-15

EGFR ligand-15 is a EGFR PROTACligand. EGFR ligand-15 can be used to synthesize PROTAC EGFR degrader MS9427 (HY-147941) .

For research use only. We do not sell to patients.

EGFR ligand-15

EGFR ligand-15 Chemical Structure

CAS No. : 295330-45-9

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EGFR ligand-15 Related Antibodies

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Description

EGFR ligand-15 is a EGFR PROTACligand. EGFR ligand-15 can be used to synthesize PROTAC EGFR degrader MS9427 (HY-147941) [1].

In Vitro

PROTAC consists of two distinct ligands linked by a linker; one is a ligand for E3 ubiquitin ligase, and the other is a ligand for the target protein. PROTAC selectively degrades target proteins by utilizing the intracellular ubiquitin-proteasome system.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

EGFR ligand-15 Related Antibodies
Molecular Weight

445.92

Formula

C22H25ClFN5O2
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

FC1=CC=C(C=C1Cl)NC=2N=CN=C3C=C(OC)C(OCCCN4CCNCC4)=CC32
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Purity & Documentation
References
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EGFR ligand-15 Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

EGFR ligand-15295330-45-9EGFR ligand15EGFR ligand 15Ligands for Target Protein for PROTACEGFRTarget Protein-binding MoietyEpidermal growth factor receptorErbB-1HER1Inhibitorinhibitorinhibit

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EGFR ligand-15
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