EGFR T790M/L858R-IN-3
EGFR T790M/L858R-IN-3 (compound B1) is a EGFRL858R/T790M inhibitor with IC50 value of 13?nM. EGFR T790M/L858R-IN-3 shows anti-tumour activity in H1975 cells with an IC50 value of 0.087 μΜ. EGFR T790M/L858R-IN-3 inhibits cell migration in A549 cells and induces apoptosis in H1975 cells.
For research use only. We do not sell to patients.
- Formula: C28H32ClN7O2S2
- Molecular Weight:598.18
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All EGFR Isoforms
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Biological Activity
Description
Chemical Information
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Molecular Weight 598.18
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Formula C28H32ClN7O2S2
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SMILES
C=C(C(NC1=CC(NC2=NC3=C(C(N4CCC5=C(C4)C=CS5)=N2)SC=C3)=C(C=C1N(CCN(C)C)C)OC)=O)Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)