ERα degrader 14
ERα degrader 14 (Compound B7) is a potent ERα degrader. ERα degrader 14 exhibits significantly potent and selective anti-proliferative activity on two ERα-positive breast cancer cell lines (MCF-7 and T47D). ERα degrader 14 induces cell cycle arrest, inhibits cell migration, and induces cell apoptosis. ERα degrader 14 effectively inhibits tumor growth in mouse models. ERα degrader 14 can be used for the study of breast cancer.
For research use only. We do not sell to patients.
- CAS No.: 2991580-03-9
- Formula: C28H24ClNO5S
- Molecular Weight:522.01
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
|
ERα |
Chemical Information
-
CAS No. 2991580-03-9
-
Molecular Weight 522.01
-
Formula C28H24ClNO5S
-
SMILES
OC1=CC=C2C(SC(C3=CC=C(O)C=C3)=C2C(C4=CC=C(O[C@@H]5CCN(C(C(Cl)C)=O)C5)C=C4)=O)=C1
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Powered by Bioz