Uracil-15N2
Based on 1 Customer Validation
Uracil-15N2 is the 15N labeled Uracil. Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA.
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- No. CAS: 5522-55-4
- Fòrmula: C4H415N2O2
- Peso molecular:114.07
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Almacenamiento:
RT, sealed storage, away from moisture and light.
In solvent -80°C, 1 year , -20°C, 6 months
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Actividad biológica
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Chemical Information
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Actividad biológica
Descripciòn
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Aplicación
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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No. CAS 5522-55-4
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Unlabeled CAS 66-22-8
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Appearance Solid
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Peso molecular 114.07
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Fòrmula C4H415N2O2
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Color White to off-white
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SMILES
O=C1[15NH]C([15NH]C=C1)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
RT, sealed storage, away from moisture and light
In solvent -80°C 1 year -20°C 6 months
Pureza y Documentación
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Ficha de datos (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instrucciones de manejo (2659 KB)
Referencias
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Pałasz A, et al. In search of uracil derivatives as bioactive agents. Uracils and fused uracils: Synthesis, biological activity and applications. Eur J Med Chem. 2015 Jun 5;97:582-611. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Uracil-15N2 Related Classifications
HY-I0960S5 Related Classifications
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