2. Vitamin D Related/Nuclear Receptor
  3. Estrogen Receptor/ERR
  4. Estrogen receptor antagonist 7

Estrogen receptor antagonist 7 (compound 13) is a potent estrogen receptors (ER) antagonist. Estrogen receptor antagonist 7 has antiproliferative activity against breast and ovarian cancer cells. Anticancer and anti-uterotrophic activities.

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Estrogen receptor antagonist 7 Chemical Structure

Estrogen receptor antagonist 7 Chemical Structure

CAS No. : 2889371-04-2

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Estrogen receptor antagonist 7 Related Antibodies

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Description

Estrogen receptor antagonist 7 (compound 13) is a potent estrogen receptors (ER) antagonist. Estrogen receptor antagonist 7 has antiproliferative activity against breast and ovarian cancer cells. Anticancer and anti-uterotrophic activities[1].

IC50 & Target

IC50: 7.2 µM in MCF-7, 11.71 µM in T-47D, 29.8 µM in SKOV-3[1]
In Vitro

Estrogen receptor antagonist 7 (compound 13) has antiproliferative activity against MCF-7, T-47D and SKOV-3 with IC50s of 7.2 µM, 11.71 µM and 29.8 µM, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Estrogen receptor antagonist 7 Related Antibodies
Molecular Weight

399.40

Formula

C23H17N3O4
CAS No.
SMILES

OC(C=C1)=CC(CCC2=C3C4=CC=C(C=C4)O)=C1C2=NN3C5=CC=C([N+]([O-])=O)C=C5
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Estrogen receptor antagonist 7 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Estrogen receptor antagonist 72889371-04-2Estrogen receptor antagonist7Estrogen receptor antagonist-7Estrogen Receptor/ERRBreast cancerovarian cancerMCF-7T-47DSKOV-3antiproliferativeanticanceranti-uterotrophicInhibitorinhibitorinhibit

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Estrogen receptor antagonist 7
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HY-143253
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