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  3. Estrogen receptor antagonist 7

Estrogen receptor antagonist 7 

Cat. No.: HY-143253
Handling Instructions

Estrogen receptor antagonist 7 (compound 13) is a potent estrogen receptors (ER) antagonist. Estrogen receptor antagonist 7 has antiproliferative activity against breast and ovarian cancer cells. Anticancer and anti-uterotrophic activities.

For research use only. We do not sell to patients.

Estrogen receptor antagonist 7 Chemical Structure

Estrogen receptor antagonist 7 Chemical Structure

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Description

Estrogen receptor antagonist 7 (compound 13) is a potent estrogen receptors (ER) antagonist. Estrogen receptor antagonist 7 has antiproliferative activity against breast and ovarian cancer cells. Anticancer and anti-uterotrophic activities[1].

IC50 & Target

IC50: 7.2 µM in MCF-7, 11.71 µM in T-47D, 29.8 µM in SKOV-3[1]

In Vitro

Estrogen receptor antagonist 7 (compound 13) has antiproliferative activity against MCF-7, T-47D and SKOV-3 with IC50s of 7.2 µM, 11.71 µM and 29.8 µM, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

399.40

Formula

C23H17N3O4

SMILES

OC(C=C1)=CC(CCC2=C3C4=CC=C(C=C4)O)=C1C2=NN3C5=CC=C([N+]([O-])=O)C=C5

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Product Name:
Estrogen receptor antagonist 7
Cat. No.:
HY-143253
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