2. Anti-infection NF-κB Metabolic Enzyme/Protease Immunology/Inflammation Cell Cycle/DNA Damage Apoptosis
  3. Fungal Reactive Oxygen Species (ROS) DNA/RNA Synthesis Apoptosis
  4. Fluoxastrobin

Fluoxastrobin is a fungicide. By binding to NAD-dependent epimerase/dehydratase, Fluoxastrobin interferes with electron transport, reduces ATP production and inhibits mycelial growth, thereby effectively controlling foliar diseases of tea plants. Fluoxastrobin induces oxidative stress by increasing ROS levels and lipid peroxidation, causes DNA damage and promotes apoptosis; meanwhile, it shows high acute toxicity to Danio rerio embryos and larvae. Fluoxastrobin can be used in research related to tea foliar diseases (including tea red leaf spot and tea gray leaf spot).

For research use only. We do not sell to patients.

Fluoxastrobin

Fluoxastrobin Chemical Structure

CAS No. : 361377-29-9

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Other Forms of Fluoxastrobin:

Fluoxastrobin Related Antibodies

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Description

Fluoxastrobin is a fungicide. By binding to NAD-dependent epimerase/dehydratase, Fluoxastrobin interferes with electron transport, reduces ATP production and inhibits mycelial growth, thereby effectively controlling foliar diseases of tea plants. Fluoxastrobin induces oxidative stress by increasing ROS levels and lipid peroxidation, causes DNA damage and promotes apoptosis; meanwhile, it shows high acute toxicity to Danio rerio embryos and larvae. Fluoxastrobin can be used in research related to tea foliar diseases (including tea red leaf spot and tea gray leaf spot)[1][2].

In Vitro

Fluoxastrobin (13.64 μg/mL) inhibits Pestalotiopsis trachicarpicola hyphal growth with an in vitro half-maximal effective concentration of 13.64 μg/mL, disrupts fungal energy metabolism via dose-dependent inhibition of ATP production and elevation of hyphal membrane potential, and binds stably to the fungal NAD-dependent epimerase/dehydratase[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Fluoxastrobin Related Antibodies
In Vivo

Fluoxastrobin (0.03-1.0 mg/L; aqueous immersion; static, daily semi-static refresh; 72-144 hours) exhibits high acute toxicity to Danio rerio embryos (96 h LC50 = 0.549 mg/L) and induces dose-dependent delayed hatching, teratogenicity, developmental impairment, oxidative stress, and DNA damage[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

458.83

Formula

C21H16ClFN4O5
CAS No.
SMILES

C(=N\OC)(\C1=C(OC=2C(F)=C(OC3=C(Cl)C=CC=C3)N=CN2)C=CC=C1)/C4=NOCCO4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Fluoxastrobin Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Fluoxastrobin361377-29-9FungalReactive Oxygen Species (ROS)DNA/RNA SynthesisApoptosis*Pestalotiopsis trachicarpicola*superoxide dismutasegray blightphytopathogenic fungiglutathione peroxidasetea leaf spot*Danio rerio*tea foliar disease pathogensNAD-dependent epimerase/dehydratasecatalaseInhibitorinhibitorinhibit

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