Fonsartan free acid
Fonsartan (HOE-720) free acid is an orally active angiotensin II receptor (AT1R) antagonist with an IC50 value of 0.48 nM, exhibiting potent antihypertensive activity. Fonsartan free acid dose-dependently inhibits angiotensin II-induced pressor response in rats (ID50 = 0.11 mg/kg) and shows significant long-lasting blood pressure-lowering effects in high-renin animal models. Fonsartan free acid is primarily used in research on hypertension and cardiovascular diseases.
For research use only. We do not sell to patients.
- CAS No.: 144628-52-4
- Formula: C26H32N4O5S2
- Molecular Weight:544.69
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Biological Activity
Chemical Information
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CAS No. 144628-52-4
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Molecular Weight 544.69
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Formula C26H32N4O5S2
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SMILES
O=C(C1=C(SC)N=C(CCCC)N1CC2=CC=C(C3=C(S(=O)(NC(NCCC)=O)=O)C=CC=C3)C=C2)O
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Synonyms
HOE-720 free acid
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Fonsartan free acid Related Classifications
HY-119379 Related Classifications
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