gamma-secretase modulator 3
Based on 1 Customer Validation
Gamma-secretase modulator 3 is a γ-secretase modulator. Gamma-secretase modulator 3 has the potential for use in research on neurological diseases such as Alzheimer's disease.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 1431697-84-5
- Formula: C24H23FN4OS
- Molecular Weight:434.53
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
Biological Activity
γ-secretase is a tetrasubunit intramembrane protease composed of presenilin, Nicastrin, APH-1, and PEN-2. It can cleave type I transmembrane proteins such as APP and Notch and participates in the pathology of Alzheimer's disease and the regulation of cell development signals.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1431697-84-5
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Appearance Solid
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Molecular Weight 434.53
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Formula C24H23FN4OS
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Color Light yellow to yellow
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SMILES
COC1=C(N2C=C(C)N=C2)C=CC(NC3=NC4=C(CCCC4C5=CC=C(F)C=C5)S3)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
DMSO : < 1 mg/mL (insoluble or slightly soluble)
Purity & Documentation
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Data Sheet (242 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)