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Cat. No.: HY-149818

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8BTC

8BTC (compound 4w) is a potent covalent Notum inhibitor with IC₅₀ of 2.5 nM.

For research use only. We do not sell to patients.

CAS No.: 3064070-24-9
Formula: C₁₀H₉Cl₂NO
Molecular Weight:230.09

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

8BTC Chemical Structure

CAS No.: 3064070-24-9

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

8BTC (compound 4w) is a potent covalent Notum inhibitor with IC₅₀ of 2.5 nM^[1].

All Wnt Isoforms :

Chemical Information

CAS No. 3064070-24-9
Molecular Weight 230.09
Formula C₁₀H₉Cl₂NO
SMILES

CC(N1CCC2=C1C=CC(Cl)=C2Cl)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Benjamin N Atkinson, et al. Designed switch from covalent to non-covalent inhibitors of carboxylesterase Notum activity. Eur J Med Chem. 2023 May 5;251:115132. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
Chemical Information
Purity & Documentation
References

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8BTC

All Wnt Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

8BTC Related Classifications

HY-149818 Related Classifications