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United States

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Referencia número: HY-149818

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8BTC

8BTC (compound 4w) is a potent covalent Notum inhibitor with IC₅₀ of 2.5 nM.

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No. CAS: 3064070-24-9
Fòrmula: C₁₀H₉Cl₂NO
Peso molecular:230.09

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

8BTC Chemical Structure

No. CAS: 3064070-24-9

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica

Descripciòn

8BTC (compound 4w) is a potent covalent Notum inhibitor with IC₅₀ of 2.5 nM^[1].

Ver todos los productos específicos de isoformas Wnt :

Chemical Information

No. CAS 3064070-24-9
Peso molecular 230.09
Fòrmula C₁₀H₉Cl₂NO
SMILES

CC(N1CCC2=C1C=CC(Cl)=C2Cl)=O
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Benjamin N Atkinson, et al. Designed switch from covalent to non-covalent inhibitors of carboxylesterase Notum activity. Eur J Med Chem. 2023 May 5;251:115132. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Actividad biológica
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Chemical Information
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8BTC

Ver todos los productos específicos de isoformas Wnt

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

8BTC Related Classifications

HY-149818 Related Classifications