Antifolate Control
-
Methotrexate γ-Methyl Ester
0 ImagesSynonyms: Methotrexate 5-methyl ester; γ-EMTXMethotrexate γ-Methyl Ester (Methotrexate 5-methyl ester) is an impurity of the folate antagonist Methotrexate (HY-14519).
-
Antifolate agent 1
0 ImagesReferencia número: HY-175428No. CAS: 518063-75-7Antifolate agent 1 is a 6-substituted pyrrolopyrimidine antifolate with a 1-carbon bridge. Antifolate agent 1 shows no activity against cells expressing FRα and FRβ, and has no GARFTase inhibitory activity. Antifolate agent 1 can be used as a negative control in the development of folate receptor-targeted antifolates.
-
(R)-Pralatrexate
0 ImagesReferencia número: HY-117791No. CAS: 1320211-70-8(R)-Pralatrexate is the (R)-enantiomer of Pralatrexate (HY-10446). Pralatrexate is an antifolate and is a potent dihydrofolate reductasean (DHFR) inhibitor.
