AA-CW236
Based on 1 Customer Validation
AA-CW236 is a MGMT (O6-methylguanine DNA methyltransferase) inhibitor. AA-CW236 targets MGMT active site Cys145 for covalent modification.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza: 99.9%
- No. CAS: 1869921-96-9
- Fòrmula: C17H16ClF3N4O2
- Peso molecular:400.78
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Almacenamiento:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Pureza y Documentación
- Referencias
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Help & FAQs
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Actividad biológica
Chemical Information
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No. CAS 1869921-96-9
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Appearance Solid
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Peso molecular 400.78
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Fòrmula C17H16ClF3N4O2
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Color White to off-white
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SMILES
FC(F)(F)OC1=CC=C(C2=C(CCl)N(CCC3=C(C)ON=C3C)N=N2)C=C1
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvente y solubilidad
DMSO : 25 mg/mL (62.38 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (268 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.4951 mL | 12.4757 mL | 24.9513 mL | 62.3784 mL |
| 5 mM | 0.4990 mL | 2.4951 mL | 4.9903 mL | 12.4757 mL | |
| 10 mM | 0.2495 mL | 1.2476 mL | 2.4951 mL | 6.2378 mL | |
| 15 mM | 0.1663 mL | 0.8317 mL | 1.6634 mL | 4.1586 mL | |
| 20 mM | 0.1248 mL | 0.6238 mL | 1.2476 mL | 3.1189 mL | |
| 25 mM | 0.0998 mL | 0.4990 mL | 0.9981 mL | 2.4951 mL | |
| 30 mM | 0.0832 mL | 0.4159 mL | 0.8317 mL | 2.0793 mL | |
| 40 mM | 0.0624 mL | 0.3119 mL | 0.6238 mL | 1.5595 mL | |
| 50 mM | 0.0499 mL | 0.2495 mL | 0.4990 mL | 1.2476 mL | |
| 60 mM | 0.0416 mL | 0.2079 mL | 0.4159 mL | 1.0396 mL |
AA-CW236 Related Classifications
HY-119390 Related Classifications
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