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ANX-M1 (Human IgG1)

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Based on 1 Customer Validation

ANX-M1 is a blood-brain barrier-permeable anti-C1q antibody. ANX-M1 can slow down the progression of retinal degeneration following photo-oxidative damage. ANX-M1 has been incorporated into nanocarriers to evaluate its brain delivery efficacy in a mouse model of Alzheimer's disease. ANX-M1 is applicable for research on age-related macular degeneration and Alzheimer's disease [1].

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  • Pureza : 99.0%
  • Peso molecular:145.78 kDa
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    Shipping with dry ice

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for ANX-M1 (Human IgG1)
  • Experimental Validation Results for ANX-M1 (Human IgG1)
  • ANX-M1 (Human IgG1) Chemical Structure
    ANX-M1 (Human IgG1) Chemical Structure
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ANX-M1 (Human IgG1) Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Encuentre su distribuidor local Your local distributor: Hycultec GmbHHycultec
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  • 1/16

    Immobilized Human C1Q Protein can bind ANX-M1 (Human IgG1). The ED50 for this effect is 56.75 ng/mL.

  • 1/16

    Flow cytometric analysis of 1X106 Hela cells labeling C1q with ANX-M1 (HY-P991886, red). Cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF488-conjugated Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • ANX-M1 (Human IgG1) Chemical Structure
    1/16
  • ANX-M1 (Human IgG1)
  • Immobilized Human C1Q Protein can bind ANX-M1 (Human IgG1). The ED50 for this effect is 56.75 ng/mL.
  • Flow cytometric analysis of 1X106 Hela cells labeling C1q with ANX-M1 (HY-P991886, red). Cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF488-conjugated Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).