Apamistamab
Based on 1 Customer Validation
Apamistamab is a CHO-expressed human antibody that targets PTPRC/CD45. Apamistamab carries a huIgG1 type heavy chain and a huκ type light chain, with a predicted molecular weight (MW) of 146.52 kDa. The isotype control for Apamistamab can refer to Human IgG1 kappa, Isotype Control (HY-P99001).
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza : 99.959%
- Peso molecular:146.112 kDa
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Almacenamiento:Shipping with dry ice
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
Descripciòn
Isotype
Human IgG1 kappa
Recommend Isotype Controls
Species Reactivity
Human
IC50 & Target
PTPRC/CD45
Ensayo clínico
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | 2011-05 | PHASE1 |
Gene ID
Accession
Conjugated
Unconjugated
Reconstitution
The product can be reconstituted/diluted with sterile PBS or saline.
Aplicación
ELISA, FACS, Functional assay
Verified Bioactivity
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Immobilized PTPRC/CD45RABC Protein, Human (HEK293, His, HY-P7887) can bind Apamistamab. The EC50 for this effect is 71.95 ng/mL. -
Flow Cytometry analysis of THP-1 cells labelling Apamistamab (red) with Apamistamab Antibody (anti-Apamistamab) (HY-P990546). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃.Human IgG1 kappa isotype Control (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
Chemical Information
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Appearance Liquid
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Peso molecular 146.112 kDa
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Color Colorless to light yellow
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Synonyms
BC-8
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Envío
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
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Ficha de datos (229 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)