BCM-599
BCM-599 is a HBV (hepatitis B virus) capsid assembly inhibitor with the activity of inhibiting HBV capsid assembly. BCM-599 showed an IC50 value of 0.88μM and a CC50 value of 144μM in HepG2.2.15 cells. When used in combination with lamivudine, BCM-599 showed a synergistic inhibitory effect on viral concentration. BCM-599 can be used as an effective combined inhibition option for HBV infection.
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- No. CAS: 1820763-99-2
- Fòrmula: C14H10Cl2FN3O2
- Peso molecular:342.15
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 2.2.15 | CC50 |
144 μM
Compound: 36; BCM-599
|
Cytotoxicity against human HepG2(2.2.15) cells after 24 hrs by MTS assay
Cytotoxicity against human HepG2(2.2.15) cells after 24 hrs by MTS assay
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[PMID: 28383274] |
Chemical Information
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No. CAS 1820763-99-2
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Peso molecular 342.15
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Fòrmula C14H10Cl2FN3O2
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SMILES
FC1=CC=C(C=C1)C(NCC(NC2=C(N=C(C=C2)Cl)Cl)=O)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
BCM-599 Related Classifications
HY-116633 Related Classifications
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