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Referencia número: HY-N21864

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Cathayanon J

Cathayanon J is a flavanone natural product with 2R configuration, which is found in the stem bark of Morus cathayana. Cathayanon J exhibits weak cytotoxicity against A549, Bel 7402, BGC-823, HCT-8 and A2780 human cancer cells, with IC₅₀ values of 4.67, 5.95, 6.70, 5.86 and 5.79 μg/mL, respectively. Cathayanon J can be used in cancer-related research.

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No. CAS: 1303438-53-0
Fòrmula: C₃₀H₃₆O₅
Peso molecular:476.60

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Cathayanon J Chemical Structure

No. CAS: 1303438-53-0

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- Cellular Effect
- In Vitro
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Classifications
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Actividad biológica

Descripciòn

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC50	4.67 μg/mL	Cytotoxicity against human lung carcinoma A549 cells assessed by MTT assay following 4-day incubation. Cytotoxicity against human lung carcinoma A549 cells assessed by MTT assay following 4-day incubation.	10286020.2010.489817
Bel-7402	IC50	5.95 μg/mL	Cytotoxicity against human liver carcinoma Bel7402 cells assessed by MTT assay following 4-day incubation. Cytotoxicity against human liver carcinoma Bel7402 cells assessed by MTT assay following 4-day incubation.	10286020.2010.489817
BGC-823	IC50	6.70 μg/mL	Cytotoxicity against human stomach carcinoma BGC-823 cells assessed by MTT assay following 4-day incubation. Cytotoxicity against human stomach carcinoma BGC-823 cells assessed by MTT assay following 4-day incubation.	10286020.2010.489817
HCT-8	IC50	5.86 μg/mL	Cytotoxicity against human colon carcinoma HCT-8 cells assessed by MTT assay following 4-day incubation. Cytotoxicity against human colon carcinoma HCT-8 cells assessed by MTT assay following 4-day incubation.	10286020.2010.489817
A2780	IC50	5.79 μg/mL	Cytotoxicity against human ovarian carcinoma A2780 cells assessed by MTT assay following 4-day incubation. Cytotoxicity against human ovarian carcinoma A2780 cells assessed by MTT assay following 4-day incubation.	10286020.2010.489817

In Vitro

Cathayanon J (0.1-10.0 μg/mL; 4 days) exhibits cytotoxicity against human cancer cell lines A549, Bel 7402, BGC-823, HCT-8 and A2780, with IC₅₀ values of 4.67, 5.95, 6.70, 5.86 and 5.79 μg/mL, respectively^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Cytotoxicity Assay^[1]

Cell Line:

human lung carcinoma (A549), human liver carcinoma (Bel7402), human stomach carcinoma (BGC-823), human colon carcinoma (HCT-8), human ovarian carcinoma (A2780)
Concentration:

0.1, 1.0, 10.0 μg/mL
Incubation Time:

4 days
Result:

Exhibited weak cytotoxic activity against human lung carcinoma (A549) cell line with an IC₅₀ value of 4.67 μg/mL.
Exhibited weak cytotoxic activity against human liver carcinoma (Bel7402) cell line with an IC₅₀ value of 5.95 μg/mL.
Exhibited weak cytotoxic activity against human stomach carcinoma (BGC-823) cell line with an IC₅₀ value of 6.70 μg/mL.
Exhibited weak cytotoxic activity against human colon carcinoma (HCT-8) cell line with an IC₅₀ value of 5.86 μg/mL.
Exhibited weak cytotoxic activity against human ovarian carcinoma (A2780) cell line with an IC₅₀ value of 5.79 μg/mL.

Chemical Information

No. CAS 1303438-53-0
Peso molecular 476.60
Fòrmula C₃₀H₃₆O₅
SMILES

O=C1C2=C(O)C=C(O)C=C2O[C@@H](C3=CC(C/C=C(C)/CC/C=C(C)\C)=C(C(C/C=C(C)\C)=C3)O)C1
Structure Classification
- Flavonoids
- Flavonones
Initial Source
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Instrucciones de manejo (2659 KB)

Referencias

[1]. Ni G, et al. Chemical constituents of the stem bark of Morus cathayana. Journal of Asian Natural Products Research. 2010;12(6):505-515.

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

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Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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