CCZ01048 TFA
Based on 4 publication(s) in Google Scholar
CCZ01048 TFA, a α-MSH analogue, exhibits high binding affinity to melanocortin 1 receptor (MC1R) with a Ki of 0.31 nM. CCZ01048 TFA shows rapid internalization into B16F10 melanoma cells and high in vivo stability. CCZ01048 TFA is a promising candidate for PET imaging of malignant melanoma.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza : 98.54%
- Fòrmula: C73H106F3N21O18
- Peso molecular:1622.75
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Almacenamiento:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Pureza y Documentación
- Referencias
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) CCZ01048 TFA
More
Actividad biológica
Descripciòn
IC50 & Target
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MC1R |
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Solid
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Peso molecular 1622.75
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Fòrmula C73H106F3N21O18
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Color White to off-white
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Sequence
DOTA-{4-amino-(1-carboxymethyl) piperidine (Pip)-Nle-CycMSHhex}
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Sequence Shortening
DOTA-{4-amino-(1-carboxymethyl) piperidine (Pip)-Nle-CycMSHhex}
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (4)
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Journal Impact Factor
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Most Recent
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Sci Rep
First-in-human dosimetry and safety evaluation of 68Ga-αMSH derivative for PET imaging of melanoma. [Abstract]2025 May 22;15(1):17748. PMID: 40404705 -
Bioconjug Chem
Radiolabeling Optimization and Preclinical Evaluation of the New PSMA Imaging Agent [18F]AlF-P16-093. [Abstract]2021 May 19;32(5):1017-1026. PMID: 33872489 -
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Iran J Immunol
Letter to the Editor Regarding "An Overview on Serology and Molecular Tests for COVID-19: An Important Challenge of the Current Century (doi: 10.22034/iji.2021.88660.1894.)". [Abstract]2022 Sep;19(3):337. PMID: 36190387
Solvente y solubilidad
In Vitro:
DMSO : ≥ 100 mg/mL (61.62 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (278 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.6162 mL | 3.0812 mL | 6.1624 mL | 15.4059 mL |
| 5 mM | 0.1232 mL | 0.6162 mL | 1.2325 mL | 3.0812 mL | |
| 10 mM | 0.0616 mL | 0.3081 mL | 0.6162 mL | 1.5406 mL | |
| 15 mM | 0.0411 mL | 0.2054 mL | 0.4108 mL | 1.0271 mL | |
| 20 mM | 0.0308 mL | 0.1541 mL | 0.3081 mL | 0.7703 mL | |
| 25 mM | 0.0246 mL | 0.1232 mL | 0.2465 mL | 0.6162 mL | |
| 30 mM | 0.0205 mL | 0.1027 mL | 0.2054 mL | 0.5135 mL | |
| 40 mM | 0.0154 mL | 0.0770 mL | 0.1541 mL | 0.3851 mL | |
| 50 mM | 0.0123 mL | 0.0616 mL | 0.1232 mL | 0.3081 mL | |
| 60 mM | 0.0103 mL | 0.0514 mL | 0.1027 mL | 0.2568 mL |
CCZ01048 TFA Related Classifications
HY-P2336A Related Classifications
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