Croconazole
Based on 1 Customer Validation
Croconazole is an antifungal agent containing imidazole rings. Croconazole has a unique structural feature of aryl vinyl at the imidazole ring N-1. Croconazole can be used for the identification and quantitative study of major metabolites in rat urine and bile .
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza: 99.24%
- No. CAS: 77175-51-0
- Fòrmula: C18H15ClN2O
- Peso molecular:310.78
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Almacenamiento:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Pureza y Documentación
- Referencias
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Help & FAQs
Actividad biológica
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Caco-2 | CC50 |
33 μM
Compound: CLOCONAZOLE
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Toxicity against Caco-2 cells determined at 48 hours by intracellular ATP concentration using the CellTiter-Glo Luminescent Cell Viability Assay
Toxicity against Caco-2 cells determined at 48 hours by intracellular ATP concentration using the CellTiter-Glo Luminescent Cell Viability Assay
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10.21203/rs.3.rs-23951/v1 |
| Caco-2 | IC50 |
18.92 μM
Compound: CLOCONAZOLE
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Determination of IC50 values for inhibition of SARS-CoV-2 induced cytotoxicity of Caco-2 cells after 48 hours by high content imaging
Determination of IC50 values for inhibition of SARS-CoV-2 induced cytotoxicity of Caco-2 cells after 48 hours by high content imaging
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10.21203/rs.3.rs-23951/v1 |
Chemical Information
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No. CAS 77175-51-0
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Appearance Solid
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Peso molecular 310.78
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Fòrmula C18H15ClN2O
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Color Light yellow to yellow
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SMILES
ClC1=CC=CC(COC2=C(C(N3C=NC=C3)=C)C=CC=C2)=C1
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvente y solubilidad
DMSO : 125 mg/mL (402.21 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (272 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.2177 mL | 16.0886 mL | 32.1771 mL | 80.4428 mL |
| 5 mM | 0.6435 mL | 3.2177 mL | 6.4354 mL | 16.0886 mL | |
| 10 mM | 0.3218 mL | 1.6089 mL | 3.2177 mL | 8.0443 mL | |
| 15 mM | 0.2145 mL | 1.0726 mL | 2.1451 mL | 5.3629 mL | |
| 20 mM | 0.1609 mL | 0.8044 mL | 1.6089 mL | 4.0221 mL | |
| 25 mM | 0.1287 mL | 0.6435 mL | 1.2871 mL | 3.2177 mL | |
| 30 mM | 0.1073 mL | 0.5363 mL | 1.0726 mL | 2.6814 mL | |
| 40 mM | 0.0804 mL | 0.4022 mL | 0.8044 mL | 2.0111 mL | |
| 50 mM | 0.0644 mL | 0.3218 mL | 0.6435 mL | 1.6089 mL | |
| 60 mM | 0.0536 mL | 0.2681 mL | 0.5363 mL | 1.3407 mL | |
| 80 mM | 0.0402 mL | 0.2011 mL | 0.4022 mL | 1.0055 mL | |
| 100 mM | 0.0322 mL | 0.1609 mL | 0.3218 mL | 0.8044 mL |
Croconazole Related Classifications
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