Defoslimod
Defoslimod (OM 174) is an agonist for TLR4 receptor and acts as an immunomodulator. Defoslimod activates macrophages and dendritic cells, induces cytokines secretion, and exhibits antitumor efficacy in rats.
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- No. CAS: 171092-39-0
- Fòrmula: C52H100N2O20P2
- Peso molecular:1135.30
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
- Pureza y Documentación
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Help & FAQs
Actividad biológica
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Macrophage | EC50 |
0.025 μg/mL
Compound: OM-174
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Induction of NO production in murine macrophage
Induction of NO production in murine macrophage
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[PMID: 17004714] |
| NCT Number | Sponsor | Condition | Start Date |
Phase
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|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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No. CAS 171092-39-0
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Peso molecular 1135.30
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Fòrmula C52H100N2O20P2
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SMILES
O=P(O)(O)O[C@H]([C@@H]([C@H]([C@@H]1O)O)NC(C[C@H](O)CCCCCCCCCCC)=O)O[C@@H]1CO[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)OP(O)(O)=O)O)NC(C[C@@H](CCCCCCCCCCC)OC(CCCCCCCCCCC)=O)=O
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Synonyms
OM 174
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Defoslimod Related Classifications
HY-164386 Related Classifications
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